It is recommended that women receiving olanzapine should not breast-feed. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks. The oral dose usually ranges from 5 mg to 20 mg. The dose of the injection usually ranges from mg to mg. Only your healthcare provider can determine the correct dose for you. Olanzapine orally disintegrating tablets must remain in their original packaging.
Open the package with clean dry hands before each dose. Do not try to put tablets in a pillbox if you take the orally disintegrating tablets. Olanzapine orally disintegrating tablets will dissolve in your mouth within seconds and can be swallowed with or without liquid. Use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication.
You may also ask a family member or a friend to remind you or check in with you to be sure you are taking your medication. The long-acting injection form of olanzapine is administered every 2 to 4 weeks.
It should be administered by your health care professional through an injection into your buttocks area. A health care professional will keep you in a setting where you can be observed for at least 3 hours after each injection. If you miss a dose of olanzapine, take it as soon as you remember, unless it is closer to the time of your next dose. Discuss this with your healthcare provider.
Do not double your next dose or take more than what is prescribed. If you miss a dose of olanzapine long-acting injection, see your healthcare provider to receive your dose as soon as possible. Avoid drinking alcohol or using illegal drugs while you are taking olanzapine.
They may decrease the benefits e. If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at Low blood pressure, drowsiness, extrapyramidal symptoms, restlessness, dizziness, headache, fatigue, insomnia, increased prolactin, weight gain, increased appetite, dry mouth, indigestion, constipation, liver function test abnormalities, weakness, accidental injury.
Olanzapine may increase the blood levels of a hormone called prolactin. Side effects of increased prolactin levels include females losing their period, production of breast milk and males losing their sex drive or possibly experiencing erectile problems. Long term months or years of elevated prolactin can lead to osteoporosis, or increased risk of bone fractures.
Some people may develop muscle related side effects while taking olanzapine. Symptoms of EPS include restlessness, tremor, and stiffness.
TD symptoms include slow or jerky movements that one cannot control, often starting in the mouth with tongue rolling or chewing movements. Temperature regulation: Impaired core body temperature regulation may occur; caution with strenuous exercise, heat exposure, and dehydration. Second generation antipsychotics SGAs increase the risk of weight gain, high blood sugar, and high cholesterol. This is also known as metabolic syndrome. Your healthcare provider may ask you for a blood sample to check your cholesterol, blood sugar, and hemoglobin A1c a measure of blood sugar over time while you take this medication.
All antipsychotics have been associated with the risk of sudden cardiac death due to an arrhythmia irregular heartbeat. To minimize this risk, antipsychotic medications should be used in the smallest effective dose when the benefits outweigh the risks. Your doctor may order an EKG to monitor for irregular heartbeat. Symptoms include confusion, fever, extreme muscle stiffness, and sweating.
If any of these symptoms occur, contact your healthcare provider immediately. All antipsychotics can cause sedation, dizziness, or orthostatic hypotension a drop in blood pressure when standing up from sitting or lying down. These side effects may lead to falls which could cause bone fractures or other injuries. This risk is higher for people with conditions or other medications that could worsen these effects.
For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to clear this drug from your body well.
This may increase the levels of olanzapine in your body and cause more side effects. This drug can also damage your liver. For people with enlarged prostate: In men, olanzapine may worsen symptoms of an enlarged prostate or benign prostatic hyperplasia BPH. If you have an enlarged prostate, talk with your doctor about whether this drug is safe for you. For people with narrow-angle glaucoma: Olanzapine may worsen your glaucoma symptoms. If you have narrow-angle glaucoma, talk with your doctor about whether this drug is safe for you.
For people with bowel problems: Olanzapine may worsen any bowel obstruction or blockages. If you have any bowel problems, talk with your doctor about whether this drug is safe for you.
For pregnant women: Olanzapine is a category C pregnancy drug. That means two things:. This drug should only be used if the potential benefit justifies the potential risk. For women who are breastfeeding: Olanzapine passes into breast milk and may cause side effects in a child who is breastfed.
Talk with your doctor if you breastfeed your child. You should decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects. All possible dosages and drug forms may not be included here.
Your dosage, drug form, and how often you take the drug will depend on:. Note: Olanzapine must be used together with fluoxetine for this condition. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Olanzapine oral tablet is used for long-term treatment of schizophrenia, and short-term or long-term treatment of bipolar I disorder. This could cause serious complications.
These include suicidal thoughts or behaviors, or thoughts of hurting others. For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:.
But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember.
But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects. How to tell if the drug is working: You should have decreased symptoms of schizophrenia, bipolar I disorder, bipolar depression, or treatment-resistant depression. A prescription for this medication is not refillable. You or your pharmacy will have to contact your doctor for a new prescription if you need this medication refilled.
You and your doctor should monitor certain health issues during your treatment. This can help make sure you stay safe while you take olanzapine. These issues include:. Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.
You may need to have blood tests or other tests during your treatment with olanzapine. The cost of these tests will depend on your insurance coverage. Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. There are other drugs available to treat your condition. Some may be better suited for you than others.
Talk with your doctor about other drug options that may work for you. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Bipolar disorder and schizophrenia are two different mental health conditions.
Find out how they're alike and how they differ. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Important : if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome. If you experience any other symptoms which you think may be due to the tablets, please speak with your doctor or pharmacist for further advice. Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital.
Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. Manufacturer's PIL, Zyprexa 2. Ltd, The electronic Medicines Compendium. Dated February Dated November
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